60 YR Male with Hematuria and Anemia




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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.


 A 60 year old male, resident of appalgudathanda suryapet district presented to OPD with chief complaints of hematuria since 2 months.

Chief complaints :


Hematuria since 2 months

Constipation since 6 days 


HOPI :


Patient was apparently asymptomatic 2 months back. Then he noticed blood in urine, which insidious in onset, gradually progressive. Increased in frequency of urine, mainly during night times for every 20 min(40-50ml) which is red in colour.

Incontinuity of urine is present, at first patient passes red colour urine along with passage of black coloured clots.

He also has history of burning micturition and suprapubic pain while passing urine.

Patient also has compliants of constipation since 6 days.


H/o giddiness.

H/o tremors .

No H/O fever, cough and cold.

No H/O nausea,vomiting,loose stools. 

No H/o orthopnea and paroxysmal nocturnal dyspnea.

No H/O abdominal distension, abdominal pain.




Past History: 


History of hydrocele, since 15 years.

He worked as a lorry driver for 20 years.

History of trauma 15 years back, while lifting the lorry back door, he slipped and fell during this. 

After this incident in 1-2 months he noticed a swelling in the right groin which is gradually increased in size, painless. Later he neglected the swelling as there was no pain.


Not a k/c/o HTN, diabetes, asthma, epilepsy, TB.

No H/O any past surgery.

He has a H/O fracture of left humerus at distal end, when he was 20 years old, while cutting a tree. Then he got treated for it with reduction and plaster of Paris. But the treatment resulted in malunion.


Personal History:


Diet: mixed

Appetite: normal

Sleep: adequate

Bowel and bladder: constipation since 6 days 

Addictions:

 Alcohol intake every day  (90ml) from 30 years, stopped 2 months back.

Smoking daily 20 beedi in 1 day from 30 years,stopped 2 months back 


Family history:


No significant history.


General examination:


Patient is conscious, coherent, and co-operative. Well oriented to time place and person.


He is moderately built and moderately nourished.

Pallor- present




Icterus- absent

Cyanosis- absent

Clubbing- absent

No lymphadenopathy

No edema


Vitals :


Temperature- Afebrile

Blood pressure- 120/80mm hg

Pulse rate- 96bpm

Respiratory rate- 20cpm


Systemic examination:


Per abdomen: 


On inspection:





Shape of abdomen: scaphoid

Umbilicus: inverted

Movements of abdominal wall with respiration

Scars present( due to beliefs that it helps in digestion, done in childhood)

Swelling in scrotum.(hydrocele?)

No visible peristalsis, pulsations, sinuses, engorged veins.


On palpation:


No local rise of temperature 

Inspectors findings are confirmed

Soft and non tender

No palpable masses

Liver is not palpable

Spleen is not palpable


On percussion:


Resonance note heard

On auscultation:

bowels sounds heard


CVS examination:


Inspection:

No raised JVP

Trachea appears to be central

The chest wall is bilaterally symmetrical 

No dilated veins, scars or sinuses are seen


Palpation:

Trachea central in position 

Apex beat is felt in the fifth intercoastal space, 1cm medial to the midclavicular line


Auscultation:

S1 S2 heardNo murmurs 

Respiratory examination:

Shape of chest is elliptical, bilaterally symmetrical

B/L airway entry positive

Normal vesicular breath sounds


CNS Examination:


Conscious 

Normal speech.

No neurological deficit found.


 DIAGNOSIS:


Severe Anemia secondary to blood loss (Hematuria) 

? Urothelial malignancy with right sided vaginal hydrocele .



INVESTIGATIONS:


16.06.23

Hemogram 


Haemoglobin - 5.1gm/dl

Total count - 9000 cells/cumm

Lymphocyte-22 %

Neutrophils-68%

Eosinophils- 10%

Basophils- 00%

Pcv- 16.2 vol%

MCV-77.7fl

MCH -24.3 pg

MCHC-31.3 %

RDW-CV - 27.1 %

RDW-SD - 78.1 fl

RBC count - 2.08 millions/cumm

Platelet count - 3.63 lakhs/cu.mm



Reticulocyte count - 3%


2D ECHO

Left ventricle- no RWMA mild LVH positive 

EF - 63%

Conclusion:

Mild TR with PAH ,trivial AR, no MR

No RWMA, No AS/MS, Sclerotic AV

Good LV systolic function

Diastolic dysfunction present

No PE/LV clot



Hemogram


Haemoglobin - 5.5gm/dl

Total count - 11,100 cells/cumm

Lymphocyte-30 %

Neutrophils-65%

Eosinophils- 0%

Basophils- 00%

Pcv- 17.6 vol%

MCV-77.4fl 

MCH -23.9pg

MCHC-30.9%

RDW-CV - 27.2 %

RDW-SD - 78.8 fl

RBC count - 2.28 millions/cumm

Platelet count - 2.5 lakhs/cu.mm




 Liver function tests
 
Total bilirubin count - 1.34 mg/dl
Direct bilirubin-0.38 mg/dl
Sgot- 16IU/l
Sgot- 15 IU/l
Alkaline phosphate- 139IU/L
Total protein -5.2gm/dl
Albumin -2.6gm/dl
A/G ratio -1.02


Haemogram

Haemoglobin - 5.0gm/dl

Total count - 9700 cells/cumm

Lymphocyte-24%

Neutrophils-65%

Eosinophils- 1%

Basophils- 00%

Pcv- 16.2 vol%

MCV-80.5fl

MCH -23.8pg

MCHC-29.6 %

RDW-CV - 20.1 %

RDW-SD - 60.4 fl

RBC count - 2.10millions/cumm

Platelet count - 2.5 lakhs/cu.mm

 

CUE

 

Colour - reddish

appearance- clear

ALBUMIN - +++

Sugars - nil

Pus cells - nil/HPF

Epithelial cells- nil HPF

Red blood cells- loaded 




15.06.23 

Review usg 


E/o 6.0*6.0 I'll defined ,hyperechoic lesion with micro calcification noted arising from the posterior wall of urinary bladder with internal vascularity .

F/s/o Urothelial malignancy



14.06.23 


USG


LIVER - Normal

Gall bladder - contracted

Pancreas - normal

Right kidney-9.7x 4.1cm -normal

Left kidney -9.5x4.2 cm -normal

AortaIVC- normal

No ascitis 

No lympadenipathy 

Urinary bladder-empty,wall thickness normal 

Prostate- pelvis could not be asseced

Spleen - 8.2cm 

    Findings-

     - spleen is showing multiple hyperechoic foci 

     -S/O gamma gland bodies 




ECG 



12-06-2023

Complete Blood picture:

HAEMOGLOBIN 4.2 gm/dl

TOTAL COUNT 9,750 cells/cumm

NEUTROPHILS 63 %

LYMPHOCYTES 28%

EOSINOPHILS 01%

MONOCYTES 08%

BASOPHILS 0%

PLATELET COUNT 4.0 lakhs /cumm

SMEAR Normocytic normochromic anemia


Prothrombin Time 16 sec

INR 1.11

BLOOD GROUP-O

RH TYPING -POSITIVE (+VE)

BLEEDING TIME - 2 Min 00 sec

CLOTING TIME -  4 Min 00 sec

APTT TEST- 32 Sec


Complete Blood Picture done on 13-6-23:

HAEMOGLOBIN 3.6 gm/dl

TOTAL COUNT 7,300 cells/cumm

NEUTROPHILS 60 %

LYMPHOCYTES 30%

EOSINOPHILS 00%

MONOCYTES 10%

BASOPHILS 0%

PLATELET COUNT 3.2 lakhs /cumm

SMEAR Normocytic normochromic anemia


16.06.23 


Referral to Urology


A 60yr old patient with right gross vaginal hydrocele with severe Anemia underwent for multiple blood transfusions having 5.0 hb percentage referred to Urology I/v/o hematuria.


Patient complains of gross hematuria since 4 months, painless hematuria present along with tissue bits. 

No fever

No pyuria

Burning micturition present 

Dysuria present 

No previous surgeries

No comorbities

H/o 44 yrs of smoking with h/ of alcoholism 


O/E 

PT is c/c/c

Afebrile 

Vitals - bp -100/60mmhg

          -PR -72bpm

         - RS - NAD

         - CVS- NAD

         -PA-NAD

Patient is advised for CECT  KUB


Advice : 

Improve general condition

Transfusions 

Tab.oflox 200 PO BD

Tab. Tranexa 500 PO BD

Tab.Pan 40 PO OD

Tab.Limcee PO OD





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